擅长炎症性肠病(溃疡性结肠炎、克罗恩病)、幽门螺杆菌相关性疾病(如慢性胃炎、消化性溃疡等)、胃食管反流病和胃肠动力障碍性疾病的临床诊治。

医疗特长：从事消化内科临床、科研和教学工作20余年，对消化系统疾病的诊断与治疗有丰富的临床经验，尤擅长炎症性肠病（溃疡性结肠炎、克罗恩病）、幽门螺杆菌相关性疾病（如慢性胃炎、消化性溃疡等）、胃食管反流病和胃肠动力障碍性疾病的临床诊治。研究方向：（1）炎症性肠病基础及临床研究；（2）幽门螺杆菌感染及其相关性疾病；（3）胃癌的遗传易感性研究。主要教育和工作经历：（1）  1984.9-1989.6: 江西医学院临床医疗系，获医学学士学位；（2）  1989.7-1993.8: 江西医学院附属第一医院消化内科，助教、住院医师；（3）  1993.9-1996.6: 中山（医科）大学附属第一医院消化内科，获医学硕士学位；（4）  1996.9-1999.6: 中山（医科）大学附属第一医院消化内科，获医学博士学位；（5）  1999.7-目前：中山大学附属第一医院消化内科，历任讲师、副教授、教授、科副主任。现为科主任、博士生导师。社会兼职：（1）中华医学会消化病学分会幽门螺杆菌学组副组长；（2）广东省医学会消化病学分会副主任委员，兼炎症性肠病学组组长；（3）广东省中西医结合学会脾胃分会常委近年发表的SCI论文：1.  Incidence and clinical characteristics of inflammatory bowel disease in a developed region of Guangdong Province, China: a prospective population-based study. J GastroenterolHepatol. 2013 Jul; 28(7):1148-53.2.  Promoter hypermethylation of BCL6B gene is a potential plasma DNA biomarker for gastric cancer. Biomarkers. 2013 Dec;18(8):721-5.3.  Epigenetic inactivation of BCL6B, a novel functional tumour suppressor for gastric cancer, is associated with poor survival. Gut. 2012 Jul;61(7):977-85.4.  Association of interleukin 1B gene polymorphism and gastric cancers in high and low prevalence regions in China.Gut. 2003 Dec;52(12):1684-9.5.  Polymorphisms in prostate stem cell antigen gene rs2294008 increase gastric cancer risk in Chinese.MolCarcinog. 2011 May;50(5):353-8.6.  IL23R +2199A/C polymorphism is associated with decreased risk of certain subtypes of gastric cancer in Chinese: a case-control study.Cancer Epidemiol. 2011 Apr;35(2):165-9. 7.  Association between the TGFB1 -509C/T and TGFBR2 -875A/G polymorphisms and gastric cancer: a case-control study.OncolLett. 2011 Mar;2(2):371-377.8.  Potential implications of mesenchymal stem cells in cancer therapy.Cancer Lett. 2011 Jun 1;305(1):8-20. Review.9.  IκBα polymorphisms were associated with increased risk of gastric cancer in a southern Chinese population: a case-control study.Life Sci. 2011 Apr 25;88(17-18):792-7. 10.  Polymorphisms in interleukin-6-6331 influences the susceptibility of a Chinese population to gastric cancer. Cancer Invest. 2011 Oct;29(8):564-72.11.  Association between polymorphisms in interleukin-17A and interleukin-17F genes and risks of gastric cancer. Int J Cancer. 2010 Jul 1;127(1):86-92.12.  IL-1B-511 polymorphism is associated with increased risk of certain subtypes of gastric cancer in Chinese: a case-control study.Am J Gastroenterol. 2010 Mar;105(3):557-64.13.  IkappaBalpha polymorphism at promoter region (rs2233408) influences the susceptibility of gastric cancer in Chinese. BMC Gastroenterol. 2010 Feb 5; 10:1514.  Contribution of rs11465788 in IL23R gene to Crohn's disease susceptibility and phenotype in Chinese population. J Genet. 2009 Aug;88(2):191-6.15.  Association of interleukin-17F 7488 single nucleotide polymorphism and inflammatory bowel disease in the Chinese population.Scand J Gastroenterol. 2009;44(6):720-6.专著：（1）  消化病临床诊断与治疗方案. 科学技术文献出版社(2010)(副主编)（2）  医学英文原版改编双语教材《内科学》. 科学出版社，编者，2007（3）  消化疾病诊断学. 人民卫生出版社, 编者, 2006（4）  内科学习题集. 军事医学科学出版社, 编者, 2005（5）  消化系统疾病治疗学. 人民卫生出版社, 编者, 2004 其他主要工作成绩（比如获奖情况）：（1）    广东省自然科学奖二等奖（主持人），2011（2）    教育部科技进步二等奖（第二完成人），2009（3）    广东省科技进步二等奖（参与），2004（4）    教育部提名的国家自然科学奖一等奖（参与），2003（5）   广东省医药卫生科技进步一等奖（参与），1996

(1) 广东省自然科学奖二等奖(主持人)，2011

(2) 教育部科技进步二等奖(第二完成人)，2009

(3) 广东省科技进步二等奖(参与)，2004

(4) 教育部提名的国家自然科学奖一等奖(参与)，2003

(5) 广东省医药卫生科技进步一等奖(参与)，1996

1. Incidence and clinical characteristics of inflammatory bowel disease in a developed region of Guangdong Province, China: a prospective population-based study. J GastroenterolHepatol. 2013 Jul; 28(7):1148-53.

2. Promoter hypermethylation of BCL6B gene is a potential plasma DNA biomarker for gastric cancer. Biomarkers. 2013 Dec;18(8):721-5.

3. Epigenetic inactivation of BCL6B, a novel functional tumour suppressor for gastric cancer, is associated with poor survival. Gut. 2012 Jul;61(7):977-85.

4. Association of interleukin 1B gene polymorphism and gastric cancers in high and low prevalence regions in China.Gut. 2003 Dec;52(12):1684-9.

5. Polymorphisms in prostate stem cell antigen gene rs2294008 increase gastric cancer risk in Chinese.MolCarcinog. 2011 May;50(5):353-8.

6. IL23R +2199A/C polymorphism is associated with decreased risk of certain subtypes of gastric cancer in Chinese: a case-control study.Cancer Epidemiol. 2011 Apr;35(2):165-9.

7. Association between the TGFB1 -509C/T and TGFBR2 -875A/G polymorphisms and gastric cancer: a case-control study.OncolLett. 2011 Mar;2(2):371-377.

8. Potential implications of mesenchymal stem cells in cancer therapy.Cancer Lett. 2011 Jun 1;305(1):8-20. Review.

9. IκBα polymorphisms were associated with increased risk of gastric cancer in a southern Chinese population: a case-control study.Life Sci. 2011 Apr 25;88(17-18):792-7.

10. Polymorphisms in interleukin-6-6331 influences the susceptibility of a Chinese population to gastric cancer. Cancer Invest. 2011 Oct;29(8):564-72.

11. Association between polymorphisms in interleukin-17A and interleukin-17F genes and risks of gastric cancer. Int J Cancer. 2010 Jul 1;127(1):86-92.

12. IL-1B-511 polymorphism is associated with increased risk of certain subtypes of gastric cancer in Chinese: a case-control study.Am J Gastroenterol. 2010 Mar;105(3):557-64.

13. IkappaBalpha polymorphism at promoter region (rs2233408) influences the susceptibility of gastric cancer in Chinese. BMC Gastroenterol. 2010 Feb 5; 10:15

14. Contribution of rs11465788 in IL23R gene to Crohn's disease susceptibility and phenotype in Chinese population. J Genet. 2009 Aug;88(2):191-6.

15. Association of interleukin-17F 7488 single nucleotide polymorphism and inflammatory bowel disease in the Chinese population.Scand J Gastroenterol. 2009;44(6):720-6.

(1) 消化病临床诊断与治疗方案. 科学技术文献出版社(2010)(副主编)

(2) 医学英文原版改编双语教材《内科学》. 科学出版社，编者，2007

(3) 消化疾病诊断学. 人民卫生出版社, 编者, 2006

(4) 内科学习题集. 军事医学科学出版社, 编者, 2005

(5) 消化系统疾病治疗学. 人民卫生出版社, 编者, 2004

(1)中华医学会消化病学分会幽门螺杆菌学组副组长;

(2)广东省医学会消化病学分会副主任委员，兼炎症性肠病学组组长;

(3)广东省中西医结合学会脾胃分会常委

(1)炎症性肠病基础及临床研究

(2)幽门螺杆菌感染及其相关性疾病

(3)胃癌的遗传易感性研究。